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Monday, May 8, 2017

A Person's Sex Is Significantly More Complicated Than One Might Expect

TRANSGENDER AGENDA FAIL: Scientists Say There Are More Than 6,500 Genes That Express Differently In Men And Women

Photo by Sander de Wilde/Corbis via Getty ImagesBelgium, Brussels, 19 May 2013. Two dressed up gay men pose in the streets of Brussels.
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Transgender activists have simultaneously detached gender completely from
sex and suggested that men can magically become "real women" by merely
 "identifying" as female, and vise-versa. This is untrue, of course. A new
 study composed by Weizmann Institute of Science researchers just widened
the hole in the transgender narrative pushed by progressives: it has been found
 that the two sexes express over 6,500 genes differently, adding to the already
 major biological differences between men and women.
"Weizmann Institute of Science researchers recently uncovered thousands of
 human genes that are expressed — copied out to make proteins — differently
 in the two sexes," notes the Weizmann Institute. The study focuses on how
"harmful mutations in these particular genes tend to accumulate in the
population in relatively high frequencies."
Professor Shmuel Pietrokovski and Dr. Moran Gershoni, both researches from
 the Weizmann Institute’s Molecular Genetics Department, "looked closely at
around 20,000 protein-coding genes, sorting them by sex and searching for
 differences in expression in each tissue. They eventually identified around
 6,500 genes with activity that was biased toward one sex or the other in at
least one tissue. For example, they found genes that were highly expressed in
the skin of men relative to that in women’s skin, and they realized that these
 were related to the growth of body hair. Gene expression for muscle building
 was higher in men; that for fat storage was higher in women," reports
Weizmann Institute. 
And the differences continue: mutations expressed in men were less likely
to be weeded out via natural selection than in women. “The more a gene
was specific to one sex, the less selection we saw on the gene. And one
more difference: This selection was even weaker with men,” said Gershoni.


The researches highlighted sexual evolution theory from the 1930's to account
 for such a difference: “In many species, females can produce only a limited
number of offspring while males can, theoretically, father many more; so the
species’ survival will depend on more viable females in the population than
 males,” said Pietrokovski. “Thus natural selection can be more ‘lax’ with the
genes that are only harmful to males.”
There were also discoveries of sex-linked genes in the mammary glands: 
Aside from the sexual organs, the researchers discovered quite a few sex-linked genes in the mammary glands — not so surprising, except that about half of these genes were expressed in men. Because men have fully fitted but basically nonfunctional mammary equipment, the scientists made an educated guess that some of these genes might suppress lactation.
While such a difference might be obvious in the mammary glands, the
researchers also found genes "to be expressed only in the left ventricle of
the heart in women. One of these genes, which is also related to calcium
 uptake, showed very high expression levels in younger women that sharply
decreased with age; the scientists think that they are active in women up to
menopause, protecting their hearts, but leading to heart disease and
osteoporosis in later years when the gene expression is shut down."
Additionally, they found "another gene that was mainly expressed in women
 was active in the brain, and though its exact function is unknown, the
scientists think it may protect the neurons from Parkinson’s — a disease
that has a higher prevalence and earlier onset in men. The researchers
 also identified gene expression in the liver in women that regulates drug
metabolism, providing molecular evidence for the known difference in drug
 processing between women and men."
“The basic genome is nearly the same in all of us, but it is utilized differently
 across the body and among individuals,” said Gershoni. “Thus, when it comes
 to the differences between the sexes, we see that evolution often works on
 the level of gene expression.”
“Paradoxically, sex-linked genes are those in which harmful mutations are
 more likely to be passed down, including those that impair fertility. From this
vantage point, men and women undergo different selection pressures and, at
east to some extent, human evolution should be viewed as co-evolution. But
 the study also emphasizes the need for a better understanding of the
differences between men and women in the genes that cause disease or
respond to treatments," added Pietrokovski. 
Still, the many intricate biological differences between men and women, such
as the ones expressed by Weizmann Institute researchers, will be said by
progressives to be simply overridden by one's feelings.